FORMULATION AND EVALUATION OF EFAVIRENZ TABLET USING MORINGA OLEIFERA AS A NATURAL POLYMER

This study describes a systemic approach for the formulation and evaluation of Efavirenz tablets has been done in this work using Moringa Oleifera as natural polymer at different concentrations. In order to identify medication, melting point, solubility, FTIR analysis were used. DSC was used investigating drug interactions. Consequently, no interaction between medicine detected. The formulations created by blending medication excipients, then analysing them Angle repose, Bulk density, Tapered bulk Hausner's ratio, Carr's compressibility index. powder blends passed all these tests with flying colours. Direct compression make seven batches pills. Thickness, hardness, friability, weight variation, content measured on manufactured tablets. All values found be within parameters. subjected in-vitro dissolving tests. Because Formulation F7 largest percentage release, it chosen best formulation. Stability performed optimised F7, findings showed significant changes throughout course three-month investigation. KEYWORDS: Efavirenz, oleifera, Formulation, Evaluation studies